Number of Nights: 10
Ship: Queen Isabel
Your journey starts in Lisbon, the city that launched some of the world's most renowned explorers. Following the Douro River through Portugal and into Spain, you'll cruise past steeply terraced hillsides, quaint villages and acres of ripe vineyards. Dine on traditional fare in majestic Coimbra, the birthplace of six Portuguese kings; enjoy private tastings of Port; and explore Porto's historic Ribeira district, home to iconic rabelo boats, cutting-edge cuisine and a thriving art scene.